Dr. Adam Collins from the University of Surrey explains the mechanism:
"Artificially maintaining GLP-1 levels several times above normal for an extended period can lead to decreased production of the body's own natural GLP-1, as well as reduced sensitivity to its action.
Once you stop taking this GLP-1 substitute, appetite is no longer controlled, and the likelihood of overeating increases significantly."
What happens after medication discontinuation:
- The body stops producing enough of its own GLP-1
- Sensitivity to the natural hormone is reduced
- Appetite returns sharply and intensified
- Compulsive eating urges emerge ("like a switch flipped")
Patients describe this state as: "It felt like something clicked in my head and said: 'Eat everything, go ahead, you deserve it, you haven't eaten for so long'"
Why Diet Gives More Sustainable Results Than Medication Without Medical Support
The research revealed a paradox:
- With diet: less weight is lost, but returns slower (0.2 kg/month)
- With GLP-1 without support: more weight is lost, but returns 4 times faster (0.8 kg/month)
Why? Because dieting forms nutrition management skills and habits that remain after completion. Medication without a medical approach simply suppresses appetite without changing the causes of weight gain.
What people taking GLP-1 independently don't get:
- Understanding of their own metabolism
- Appetite management skills without medication
- Exit strategy and weight maintenance plan
- Correction of metabolic and hormonal causes of weight gain
Warning From Oxford University Researcher
Dr. Susan Jebb from Oxford University warns:
"People who buy these drugs need to remember the risk of rapid weight regain after treatment ends."
She emphasizes: these are medical trial data. In real practice, the situation may be even more complex, as people often:
- Don't undergo medical assessment before starting
- Don't receive nutrition and lifestyle recommendations
- Abruptly stop taking medication upon reaching desired weight
- Have no result maintenance plan
Why Med4Slim Is Not Just a Medication
Unlike self-administration of GLP-1, a medical weight loss program includes exactly what prevents rapid weight regain:
- Working with causes of weight gain (hormones, metabolism, insulin resistance)
- Habit formation for nutrition management without medication
- Gradual exit from medication with body adaptation
- Weight maintenance plan after program completion
- Specialist team support (doctor, dietitian, psychologist)
BBC research confirms: without a comprehensive approach, GLP-1 is a temporary solution with high rebound risk.
Conclusions
British Medical Journal data and BBC analysis are clear: after GLP-1 discontinuation without medical support, weight returns 4 times faster than after dieting.
The reason is lack of metabolic work, habit formation, and exit strategy. A medical weight loss program solves exactly these issues and helps maintain results long-term.
